Research Focus Areas
Listed alphabetically by subject area. Please send updates to mrattana@health.ucsd.edu.
4D Nucleome Research
Aging
Molecular mechanisms of aging; impact of inflammation on the brain; chronic diseases of aging.
Allergy and Immunology
Molecular and cell biology of allergy; immune-mediated and inflammatory diseases; mucosal immunity.
Angioedema
- Division of Rheumatology, Allergy & Immunology
- Bruce Zuraw, MD, chief of the division and inaugural holder of the US Hereditary Angioedema Association (HAEA) Endowed Chair and director of the first U.S. HAEA Angioedema Center at UC San Diego Health.
Arthritis and Inflammatory Disease
Pathogenesis and treatment.
Asthma/COPD
- Clinical Trials Center
- Division of General Internal Medicine
- Division of Physiology
- Division of Pulmonary, Critical Care & Sleep Medicine
- Alpha 1-Antitrypsin Deficiency - UC San Diego is an Alpha-1 Foundation Clinical Resource Center
- Division of Rheumatology, Allergy and Immunology
Atherosclerotic Heart Disease
Bioengineering
Biomedical Informatics
Bioinformatics; clinical informatics; global health informatics and telemedicine; infrastructure, privacy technology and health information exchange.
Core bioinformatics expertise to manage and analyze large molecular datasets, especially from next-generation sequencing. Special emphasis in genomics, systems biology and personalized medicine.
Bone Marrow Transplantation
Cancer
Cardiology
Atherosclerosis; cardiac electrophysiology; cardiac mechanics; heart failure; integrins in inflammation; interventional cardiology; molecular cardiology; physiology and pharmacology.
Clinical Decision Support
Clinical Trials
- Center for Innovative Therapy
- Clinical and Translational Research Institute - Studies Recruiting Volunteers
- Clinical Trials Office at the Moores Cancer Center
Dementia
Diabetes
Etiology, treatment, and prevention; molecular mechanisms; pathogenesis of diabetic kidney disease; the contribution of the kidney to cardiovascular disease in diabetes and obesity.
- Institute for Diabetes and Metabolic Health
- Division of Endocrinology and Metabolism
- Division of Nephrology-Hypertension
- Novel Paradigms in Diabetic Complications (NIH Type 1 Diabetes Targeted Research Award)
- Center for Metabolic Research, VA San Diego Healthcare System
- Glycemic control in inpatients
- Division of Hospital Medicine
- Sanford Stem Cell Clinical Center
Digestive Diseases
Celiac disease; gastrointestinal infection; intestinal inflammatory disease.
- Division of Gastroenterology
- Endoscopic Research
- Colon cancer screening quality improvement
- Pancreatic cancer diagnosis and prevention
- New endoscopic devices
- Natural orifice translumenal endoscopic surgery (NOTES)
- Small intestinal imaging
- Endoscopic treatment of early esophageal cancer
Endocrinology and Metabolism
Obesity; lipid research; pituitary; thyroid; signal transduction; transcription; calcium and bone; reproductive endocrine diseases.
Endoscopy & Gastroenterology
Genomic Medicine
Geriatrics
Molecular mechanisms of aging; impact of inflammation on the brain.
Global Public Health
HIV/AIDS, malaria, tuberculosis; risk factors, transmission, treatment, prevention, border health, health care utilization, STDs, viral hepatitis, substance use, migration and health, and social justice.
Glycobiology
Heart Failure
Hematology-Oncology
Experimental therapeutics; hematological malignancies; chronic lymphocytic leukemia; stem cell biology; tumor biology/immunology; hematopoiesis; platelet-vascular biology.
Hepatitis
Hepatology
HIV/AIDS
Pathogenesis, prevention, risk factors, transmission, treatment.
- AIDS Research Institute
- HIV research, bioinformatics and information technologies - Douglas D. Richman, MD, Director, AIDS Research Institute
- Antiviral Research Center
- UCSD Department of Medicine HIV/AIDS Clinical Trials Unit (NIH Cooperative Agreement)
- Center for AIDS Research (NIH Research Center Core Grant)
- Division of Infectious Diseases & Global Public Health
- Training Program in Substance Use, HIV and Related Infections (NIH Training Grant)
- Active Projects
Hospice
Hospital Medicine
Glycemic control, venous thromboembolism prevention, transitions of care.
- Division of Hospital Medicine
- Innovations Reducing Hyper- and Hypoglycemic Events in Inpatients (NIH Research Demonstration/Dissemination Project)
Hypertension
Infectious Diseases
HIV and opportunistic infections; drug resistance; hepatitis B and C; Leptospira; malaria; tuberculosis; microbial pathogenesis; international medicine; neurovirology; prevention; tropical medicine; parasitology.
- Division of Gastroenterology
- Division of Infectious Diseases & Global Public Health
- HIV Neurobehavioral Research Center
- Division of Pulmonary, Critical Care and Sleep Medicine
See Also HIV/AIDS
Inflammatory Bowel Disease
Developing new biotechnology therapies; conducting multicenter clinical trials; clinical pharmacology of medications used in treatment.
See Also Digestive Diseases
Kidney Disease / Kidney Injury
Development; physiology and pathophysiology; hypertension; immuno-pathogenesis and transplantation; function in early diabetes and diabetic nephropathy; acute injury and outcomes research; failure.
- Division of Nephrology-Hypertension
- Acute Kidney Injury Research
- Diabetic Kidney Disease
Leukemia, Myeloproliferative Disorders
Cancer clinical trials, cellular-immunotherapy, diagnostics, experimental therapeutics, gene immunotherapy, regenerative medicine, stem cell medicine, tumor biology.
Lipid Research
Liver Disease
Epidemiology and biomarkers for liver disease; multi-targeted therapies for liver cancer; molecular pathogenesis of fibrotic liver disease and the genetic basis of liver disorders;
progression of chronic liver diseases; hepatic fibrosis; alcoholic liver disease; liver failure; hepatitis B and C; clinical trials; treatments; transplantation; population screening; vaccination.
Medical Genetics
Genomics and personalized medicine; systems biology.
Division of Medical Genetics
- Trey Ideker, PhD
- NDEx - The Network Data Exchange, A Network Commons for Biologists
- A Systems Approach to Mapping the DNA Damage Response
- Cytoscape, A Modeling Platform for Biomolecular Networks
- Comparative Analysis of Genetic Interaction Networks
- National Resource for Network Biology
- San Diego Center for Systems Biology: From Maps to Models
- Systems Biology and Integrative Networks Core, Chronic HIV Infection and Aging in NeuroAIDS (CHAIN) Center
- Jill Mesirov, PhD
- GenomeSpace data analysis platform
- Network Approaches to Identify Cancer Drivers from High-Dimensional Tumor Data (NIH Early Independence Award to Hannah Carter, PhD)
- Training Program in Basic and Clinical Genetics (NIH Training Grant)
Nonalcoholic Fatty Liver Disease (NAFLD)
- NAFLD Research Center led by Rohit Loomba, MD, MHSc, Division of Gastroenterology and Hepatology
Obesity
Palliative Medicine
Pancreatic Cancer
- UC San Diego Health Researchers Join Pancreatic Cancer "Dream Team" - Department of Pharmacology, Skaggs School of Pharmacy and Pharmaceutical Sciences; Department of Medicine and Department of Surgery; Moores Cancer Center
- Division of Gastroenterology and Hepatology
Pulmonary and Critical Care Medicine
COPD; drug-resistant tuberculosis; pulmonary function during weightlessness; respiratory biology; sleep medicine.
See Also Division of PhysiologyRegenerative Medicine
- Moores Cancer Center
- Division of Regenerative Medicine
- Sanford Stem Cell Clinical Center and Sanford Consortium for Regenerative Medicine
Rheumatic Diseases
Biology of immunologic and inflammatory diseases; pathogenesis and treatment of rheumatoid arthritis.
Sleep Medicine
The pathogenesis of sleep apnea; metabolic/cardiovascular complications of sleep disorders; mechanical ventilation in acute respiratory distress syndrome.
Smoking and Health
Systems Biology
Tuberculosis
Vascular Diseases and Thrombosis
Deep vein thrombosis; chronic thrombotic venous disease.
- Division of Pulmonary, Critical Care and Sleep Medicine
- Division of Rheumatology, Allergy, and Immunology
DVT prevention in inpatients: